Paracetamol risk: EU watchdog demands urgent review over new side effect

The European Medicines Agency (EMA) has dropped a bombshell about one of the world’s go-to remedies for aches and pains.

Paracetamol, the pharmacy favourite found in nearly every home, now comes with a shocking new warning: it could lead to a dangerous condition called metabolic acidosis if misused or overused.

What are the dangers of paracetamol?

The EMA’s Pharmacovigilance Risk Assessment Committee (PRAC) has sounded the alarm, urging an update to the drug’s safety leaflet to include this newly highlighted side effect. Whether you’re popping paracetamol solo or taking it as part of a combo treatment, the risk applies across the board.

Metabolic acidosis, specifically the high anion gap type (HAGMA), occurs when the body becomes too acidic. Left unchecked, this condition could spiral into serious complications like kidney failure, sepsis, or depleted glutathione levels – especially in chronic drinkers.

Symptoms not to ignore

The EMA warns that symptoms of HAGMA can include:

• Difficulty breathing, often rapid and deep
• Extreme drowsiness
• Persistent nausea or vomiting

If you or someone you know experiences any of these after prolonged paracetamol use, stop taking the drug immediately and seek medical advice. Doctors will likely order tests and keep a close eye on you during recovery.

Time for a dose of caution when taking paracetamol

Paracetamol, long considered a harmless household staple, is now facing a sobering review. While the drug is generally safe when used as directed, experts stress the importance of sticking to the recommended doses and avoiding long-term or excessive use.

This isn’t the first time paracetamol has come under scrutiny, but with the EMA’s new findings, the days of casually reaching for the packet might be over.

Stay informed, and remember: when it comes to your health, there’s no harm in double-checking.

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